In season 5, at the start, Dr. Chang told the worker to not drill any further into the wall, because they will hit a pocket of energy and “all hell would break loose”.
I think at the end of season 5, it wasnt an explosion, it was a flash. I think the bomb did infact explode, but all it did was open up the energy underneath the future Swan station.
So what I am saying is, I think it was a flash, which would lead to a number of things – Jacob perhaps alive again, Juliet perhaps alive again (if she is infact dead), Locke alive again. But I do not know what will happen to the MIB?